Main description

1.  YGF-5 automatic pre-filling injector filling line, using manual to outsource bag, and the automatic opening of the inner package robot and the technology of paper absorbing, automatic pretreatment for the back filling of the preparation work.

2.  FFR automatic prefilling injector filling line, using manual to outsource bag, and the automatic opening of the inner package robot and the technology of paper absorbing, automatic pretreatment for the back filling of the preparation work.

3.  Adopted advanced high-precision linear peristaltic pump filling, and the servo motor and module transmission of filling system in order to achieve the ability of high precision and stability, after filling and sealing stopper is synchronous, using sensors to ensure the system each next process are accurate, the vibration of the rubber plug with a fully automated and vibrator technology, make the whole process of Richard stopper is efficient, the electrical on the use of advanced sensor systems and advanced motion controller technology, can guarantee the stability of the system with high precision, this prefilled syringe filling and sealing technology has reached the advanced level.

4.  YGF - 5 automatic prefilled syringe filling line, USES the manual removal of outer packing plastic bags - air brake interlocking conveying to tear material box sealing membrane, the material of paper inside the box suck - transport: hand syringe - syringe barrel filling liquid - syringe barrel sealing stopper - bin - automatic transmission - sliding down into the receiving platform such as technology, technology of the equipment is sterile syringe in A level within the region.

5.  The advanced straight-line peristaltic pump filling can achieve high accuracy, and the servo motor and module drive to reach the filling system

6.  The ability of high accuracy and stability, sealing with glue plug after filling.

Working principle

1.  YGF - 5 automatic prefilled syringe filling line, uses the manual removal of outer packing plastic bags - air brake interlocking conveying to tear material box sealing membrane, the material of paper inside the box suck - transport: hand syringe - syringe barrel filling liquid - syringe barrel sealing stopper - bin - automatic transmission - sliding down into the receiving platform such as technology, technology of the equipment is sterile syringe in A level within the region.

2.  The advanced straight-line peristaltic pump filling can achieve high accuracy, and the servo motor and module drive to reach the filling system.

3.  The ability of high accuracy and stability, sealing with glue plug after filling

Main features

1.  Adopted advanced high-precision linear peristaltic pump filling.

2.  The servo motor and module transmission of filling system in order to achieve the ability of high precision and stability, after filling and sealing stopper is synchronous, using sensors to ensure the system each next process are accurate, 

3.  The vibration of the rubber plug with a fully automated and vibrator technology, make the whole process of Richard stopper is efficient

4.  The electrical on the use of advanced sensor systems and advanced motion controller technology, can guarantee the stability of the system with high precision, this prefilled syringe filling and sealing technology has reached the advanced level.

Workshop layout

Step 1: Manually remove outside package

1.  Manually put the syringe with aseptic bag to protect nest box in the cutting location, through the outer garment bag gloves will nest fixed box on outsourcing cutting station, the operator hand touch switch to cut (knife in inside to avoid the dangerous damage and easy replacement).

2.  Manually cut out nest box aseptic bag, hold down the button manually, open the door, put into the B room, the nest box when bin charter flights leave away, hold down the button manually, turn off the glass door, bags and other waste by waste boxes outside.

3.  Feeding landslide plant design in the left-hand side, convenient feeding box, and the feed slide device can ensure more than four boxes with quantity.

Step 2: Air interlocking process

1.  When bin reaches the end of the conveyor, and the sensor detects the position here, discharging automatic door open.

2.  when another sensor detected bin in place after the discharge automatic doors off.

3.  After takeoff the outer packing material box, in the period of the buffer self-purification, avoid pollution packet bag.

4.  When the pressure gauge on the laminar flow, according to a damper interlocking airflow pressure than manual away on the air pressure on the package, you won't get air flow backward.

5.  Part of air interlocking device the conveyor belt into the wall (inside the walls not stretched out), and enter a part of the wall is a steel covering, and steel sheet good air tightness will not leak.

6.  Device containing active ORABs, mixed in Grade A environment.

Step 3:Automatic opening inner package process

1.  Bin after entering conveyor is blocked to book (A number positioning), 2 sensors detect the material box after putting in place, release bin forward delivery.

2.  Near the manipulator is blocked when going to a locating mechanism of (B), 3 sensors in place after the conveyor to stop delivery, bin two diagonal gas claw clutch is not to let it move, manipulator moves material box sealing membrane on the surface of the tear, to waste and put it into the collection box, then suck up automatically the paper into the waste collection box, and then air claw let go, release the material box, conveyor transporting, other all mechanism with cylinder automatic reset function.

3.  Device containing active ORABs, mixed in Grade A environment.

Step 4: Transshipment, filling and sealing process

1.  Bin after the transition to the section on the conveyor, forward conveying material box, to transfer the hand near the cylinder to set its position, transshipment hand grabbed the whole plate of syringe into the Y on the conveyor, to release material box, and X Y conveyor synchronization work entered, filling the whole plate of syringe to lower part of the needle, a filling 5 needles, and then the vibration plate manage good five immediately synchronized to the mouth of the syringe stopper is sealed, so the cycle until the whole plate sealed finish all syringe filling and rubber plug, and X Y conveyor synchronization work output bin, robots will be the whole plate of syringe into 6 place the positioning of the material box, and then release material box of output.

2.  Device containing active ORABs, mixed in grade A environment.

3.  Liquid 2-3L is glass, can a mouth into the liquid, liquid out of the other five.8 l have magnetic stirring mixing liquid buffer tank bottom, CIP and SIP, when detecting jar without liquid, can automatic control of pneumatic valves open make solution to come in, the other also have a manual valve can manual control fluid in and out. The 50L can also carry CIP and SIP.

4.  The filling accuracy is not more than five over one thousand of the peristaltic pump, the easiest to implement online SIP and CIP, repackaging range from 0.1 to 46 ml, large quantities of repeat packaging of high stability, delayed start-up can be set up to prevent fly base or bubble phenomenon, also can realize the stop and back to prevent drip, absorption material liquid do not contact with equipment, no dead Angle in all directions, conform to the hygienic requirements.

5.  Each pump by an independent servo motor control, can adjust the filling quantity, alone and with functions of menu type load selection.

6.  Filling needle movement is controlled by the servo motor, can control the filling needle and medicine rise.

Step 5 Vacuum stopper adding device

1.  Syringes, plunger and ventilation plate fixed die, plunger plate with two independent servo motor control and ventilation, sealing plate is installed on the coat.

2.  Stopper is crowded, and coat plate extrusion ventilation in the sealing ring, sealing ring make contact won't leak after deformation, therefore the ventilation plate cavity will not leak.

3.  Plunger downward movement to press the rubber plug into to the stopper is packed inside, rubber plug into the internal compression deformation, the deformation of contact surface will not leak.

4.  Ventilation board downward movement, with its downward movement of seal, elastic silicon material sealing disc pressure syringe and deformation, change shape after the contact surfaces of the two will not leak.

5.  When to the bleeding point extraction, due to the rubber plug with no leakage between injector chamber, when after the rubber plug at the bottom of the air pump, rubber plug is in atmospheric pressure down into the syringe.

6.  In a fine-tuning valve leakage, piping installation series again by a vacuum gauge control solenoid valve; Use solenoid valve when necessary to make true air conditioning, and set vacuum control range on vacuum gauge. Set when the vacuum chamber reaches the limit, vacuum instrument through to the power of the electromagnetic valve and nitrogen by fine-tuning valve and solenoid valve leakage into the cavity in the body, the amount of gas leakage into the should be adjusted by fine-tuning valve leakage. If the regulation too general assembly causes too much gas to leak, so that the cavity pressure rises too much, even a vacuum alarm will occur; If the regulation is too small, the gas is too small, the pressure does not rise or rise slowly. The appropriate air leakage should be adjusted when the solenoid valve is opened. The pressure will rise slowly and the solenoid valve will be closed and the gas will stop entering the cavity.

7.  Vacuum tube with one-way valve, which has the effect of intrusion prevention, additional vibration plate of rubber plug has the effect of filter, allows only one side of the stopper is by rail, negative fall into the disc, equipment has a rubber plug turn-over device.

8.  Filling nitrogen charging protection function is designed.

Step 6: Automatic sampling and weighting device

1.  Begin from filling machine on the assembly drawing of the automatic sampling weighing device on them, and no interference with other structures, the nest plate and syringe positioning in the X and Y the two horizontal and vertical can be moved on the module, you can adjust the nest plate on the injector hole, and take samples of the five-hole position is in horizontal direction is consistent.

2.  Nest plate with syringe after horizontal and vertical movement, the first landscape syringe five syringe (as shown) is located in the top down to the bottom of the bottle of lifting cylinder, top the five bottles of lifting cylinder injector jacking, then servo motor control slider to move right.

3.  Nest plate and syringe horizontal and vertical movement, according to the previous action will the inside of the nest plate 100 syringe after weighing, the weight of the equipment to record these 100 bottles, including 1 to 20 bottles of 1 is the weight of the pump to fill the no. 21 to 40 bottles of no. 2 is the weight of the pump to filling, 41 to 60 # 3 is the weight of the pump bottle filling of 61 to 80 bottles is the weight of the pump to fill 4, 80 to 100 bottles of 5 is the weight of the pump to filling, the weight of the equipment to record these 100 bottles with the serial number of the 100 bottles, five time scales shorter than 1 time scales, the other only when the wind vibration after offset, such as zero balance weight to weigh.

4.  After the nest plate with the filling syringes, and then to weigh, 100 bottles of the balance at the moment and the weight of the liquid, to record the 100 bottles of dosing device with the serial number of the 100 bottles, the weight of the weight minus the weight of the bottle is useful data, through the analysis of the fluctuations of these useful data size will know those five pumps filling accuracy of each equipment.

5.  Breathing bag of rubber plug in the buffer after class A laminar self-purification, hand through the glove box unpacking will pour into buffer hopper stopper, buffer hopper slope, rolling down from slope, the stopper is adhesive on the vibration plate automatic feeding.

Step 7: Turnable door

1.  Because the whole filling line across the entire filling workshop, people enter the filling workshop, must often through the device, so the design for the turn-over device, when people to cross, you only need to flip components, can easily through the rotation Angle.

2.  In order to reduce the weight without motor, it is natural to slide down slope, and use nylon to reduce weight.

3.  In addition to prevent pollution, normal oil-gas gate is closed, so it will be between filling and buffer space, only when the sensors have bin in place, gas valve open to bin from filling into the buffer room between the valve closes when the buffer is detected to enter the material box.

4.  When the sensor detects that the material box accumulates too much, the equipment stops.

Step 8: Conveyor device process

1.  The main function of this segment is to transport the material box out of the buffer room.

2.  In addition to prevent pollution, normal oil-gas gate is closed, so will the buffer room with CNC interval, only when the sensors detect the material box in place, gas valve open to bin from the buffer room into CNC. The valve closes when the box is detected.

3.  In addition, this section is long, if all used slope, the final box is very low to the ground, not convenient for the rear of the manual to take the injector to take the slot or automatically remove the slot.

Step 9: Process flow of receiving platform

1.  Bin from the buffer room, into the platform slope plate, tablet, the gravity drops into platform on three sides have guard bin don't let it out, blocking platform at least material box can hold more than 5 boxes.

2.  Or, after coming out of the buffer, the syringe is removed from the slot.